A major focus of Siyakhana has been the implementation of a multi and interdisciplinary approach to the complex problem of food security. Siyakhana has mobilised and collaborated with the following diverse range of international and national tertiary institutions, national, provincial and local government, and community based organisations in order to most effectively address food security, environmental sustainability and social equity.

• Gauteng Department of Agriculture, Conservation and Environment
• Gauteng Department of Health and Social Development
• Gauteng Department of Economic Development
• Joburg Department of Social and Human Development
• Joburg Department of Environment and City Parks•
• WITS Departments of Civil and Industrial Engineering
• WITS Animal Plant and Environmental Sciences Unit
• WITS Department of Architecture & Planning
• Wits Department of Geography and Environmental Sciences
• Wits School of Pharmacology
• WITS Enterprise
• Food & Trees for Africa
• REOS
• African Food Security Urban Network (AFSUN)
• Ekukhanyeni
• South African National Tuberculosis Association (SANTA)